Periventricular Leukomalacia

Periventricular Leukomalacia

What is this error ?


  1. Reply

    Periventricular area is so critical because it contain germinal maturix which is the site for neuronal migration, so any adverse effect lead to unfavorable out come

  2. Reply

    Germinal matrix is risky because it contain loose connective tissue, abundant blood vessels, near to the ventricle, & poorly developed in pretem, so any changes in intracranial pressure, bleeding disorder or sepsis lead to germinal matrix hemorrhge.

  3. Reply

    The injured cells in that area healed by gliosis may be later on liquified lead to multiple cyst.

  4. Reply

    Bad development of germinal matrix and neuronal migration lead to upper motor neuron lesion usually in form of spastic quadiplegia.

  5. Reply

    IT is one of complication of Prematurity

  6. Reply

    The incidence of that error inversly proportionate to age of premature

  7. Reply
    mariem abd el samee

    if ventilated neonate specially preterm and pressure of mechanical ventilation changed rapidly and not gradual IVH may happend

  8. Reply
    mariem abd el samee

    if ventilated neonate and massive pneumothorax happend IVH may be a complication

  9. Reply
    mariem abd el samee

    surfactant therapy with bad management also may be a cause of IVH is that correct or not????????

    • Reply

      Caused by hypoxia-ischemia with particular vulnerability of premature brain and usually diagnosed in neonatal period by cranial US

  10. Reply

    PVL is a type of brain is most common in preterms more that fullterms .it is common in infant before 32 week. Infants who have IVH are at more risk for developing PVL .it is one of complication of prematurity. Infants who have this condition suffer from motor developemental delay , cerebral palsy or epilepsy later in their life.

  11. Reply
    Lamiaa rehan

    Periventricular leukomalacia is a type of brain injury that affects premature infants. The condition involves the death of small areas of brain tissue around fluid-filled areas called ventricles. The damage creates “holes” in the brain. “Leuko” refers to the brain’s white matter. “Periventricular” refers to the area around the ventricles.

    PVL is much more common in premature infants than in full-term infants.
    A major cause is thought to be changes in blood flow to the area around the ventricles of the brain. This area is fragile and prone to injury, especially before 32 weeks of gestation.
    Infection around the time of delivery may also play a role in causing PVL. The risk for PVL is higher for babies who are more premature and more unstable at birth.
    Premature babies who have intraventricular hemorrhage are also at increased risk for developing this condition.

  12. Reply
    Amal Gaber

    Peri ventricular leuokomalcia is the most important complication of prematurity its outcome detrimen how will be the future life of this baby

  13. Reply
    Amal Gaber

    Usually occur in extremely premature as a complication of mechanical ventilator support

    • Reply
      Safaa ELMeneza

      Yes I agree ,it can also related to low blood pressure ,inadequate oxygenation

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