Periventricular area is so critical because it contain germinal maturix which is the site for neuronal migration, so any adverse effect lead to unfavorable out come
Germinal matrix is risky because it contain loose connective tissue, abundant blood vessels, near to the ventricle, & poorly developed in pretem, so any changes in intracranial pressure, bleeding disorder or sepsis lead to germinal matrix hemorrhge.
PVL is a type of brain injury.it is most common in preterms more that fullterms .it is common in infant before 32 week. Infants who have IVH are at more risk for developing PVL .it is one of complication of prematurity. Infants who have this condition suffer from motor developemental delay , cerebral palsy or epilepsy later in their life.
Periventricular leukomalacia is a type of brain injury that affects premature infants. The condition involves the death of small areas of brain tissue around fluid-filled areas called ventricles. The damage creates “holes” in the brain. “Leuko” refers to the brain’s white matter. “Periventricular” refers to the area around the ventricles.
Causes
PVL is much more common in premature infants than in full-term infants.
A major cause is thought to be changes in blood flow to the area around the ventricles of the brain. This area is fragile and prone to injury, especially before 32 weeks of gestation.
Infection around the time of delivery may also play a role in causing PVL. The risk for PVL is higher for babies who are more premature and more unstable at birth.
Premature babies who have intraventricular hemorrhage are also at increased risk for developing this condition.
15 Comments
Monmon
Periventricular area is so critical because it contain germinal maturix which is the site for neuronal migration, so any adverse effect lead to unfavorable out come
Monmon
Germinal matrix is risky because it contain loose connective tissue, abundant blood vessels, near to the ventricle, & poorly developed in pretem, so any changes in intracranial pressure, bleeding disorder or sepsis lead to germinal matrix hemorrhge.
Monmon
The injured cells in that area healed by gliosis may be later on liquified lead to multiple cyst.
Monmon
Bad development of germinal matrix and neuronal migration lead to upper motor neuron lesion usually in form of spastic quadiplegia.
Monmon
IT is one of complication of Prematurity
Monmon
The incidence of that error inversly proportionate to age of premature
mariem abd el samee
if ventilated neonate specially preterm and pressure of mechanical ventilation changed rapidly and not gradual IVH may happend
mariem abd el samee
if ventilated neonate and massive pneumothorax happend IVH may be a complication
mariem abd el samee
surfactant therapy with bad management also may be a cause of IVH is that correct or not????????
Seham
Caused by hypoxia-ischemia with particular vulnerability of premature brain and usually diagnosed in neonatal period by cranial US
Amani
PVL is a type of brain injury.it is most common in preterms more that fullterms .it is common in infant before 32 week. Infants who have IVH are at more risk for developing PVL .it is one of complication of prematurity. Infants who have this condition suffer from motor developemental delay , cerebral palsy or epilepsy later in their life.
Lamiaa rehan
Periventricular leukomalacia is a type of brain injury that affects premature infants. The condition involves the death of small areas of brain tissue around fluid-filled areas called ventricles. The damage creates “holes” in the brain. “Leuko” refers to the brain’s white matter. “Periventricular” refers to the area around the ventricles.
Causes
PVL is much more common in premature infants than in full-term infants.
A major cause is thought to be changes in blood flow to the area around the ventricles of the brain. This area is fragile and prone to injury, especially before 32 weeks of gestation.
Infection around the time of delivery may also play a role in causing PVL. The risk for PVL is higher for babies who are more premature and more unstable at birth.
Premature babies who have intraventricular hemorrhage are also at increased risk for developing this condition.
Amal Gaber
Peri ventricular leuokomalcia is the most important complication of prematurity its outcome detrimen how will be the future life of this baby
Amal Gaber
Usually occur in extremely premature as a complication of mechanical ventilator support
Safaa ELMeneza
Yes I agree ,it can also related to low blood pressure ,inadequate oxygenation